Wellbutrin, a drug manufactured by Glaxo Wellcome Inc., is an antidepressant also known as bupropion. This antidepressant has has been approved by the US Food and Drug Administration, or FDA, for treating depression in men and women. Wellbutrin has also been prescribed for the treatment of ADHD, or attention-deficit hyperactivity disorder, as well as SAD, or seasonal affective disorder. Bupropion is the chemical name for Wellbutrin, and is also sold using the brand name of Zyban, as a medication to stop smoking.
Wellbutrin is a dopamine-re-uptake blocking compound, and has a chemical make-up different from other anti-depressants offered such as Prozac and Zoloft. These other antidepressants target the chemical serotonin found in the brain, while Wellbutrin affects the chemicals in the brain known as dopamine and norepinephrine. Many people who have not had previous success with other antidepressants have found that Wellbutrin works better.
As with any drugs, there are risks of side effects when taken. With Wellbutrin, there are less sexual side effects as well as lesser weight gain reported as with other antidepressants. Fewer reports of dry mouth, blurred vision and constipation have also been reported from those on this medication. Additionally, there have been fewer reports of cardiac problems and orthostatic hypertension, as well. Common side effects that can occur with Wellbutrin are trouble sleeping, headaches, nausea, tremors, dry mouth, increased heart rate, rashes, restlessness, agitation and dizziness.
Reports of Wellbutrin causing seizures caused the drug to be temporarily taken off of the market after the initial release of the drug. After deeper investigation into these cases, it was determined that these seizures were associated with those who took very high doses of the drug- above the daily recommended dosage of 450 mg per day. Seizures were also associated with those who already had a history of seizures or brain trauma, as well as those who suffered from an eating disorder, abused alcohol or took other drugs that had a risk of seizures. The chance of seizures have been reduced dramatically after newer warnings were put on the drug Wellbutrin, as well as lower dosages recommended.
Wellbutrin can only be described by a licensed doctor, and those on the drug should be closely monitored while taking it. The standard dose of Wellbutrin begins at 100 mg twice a day, and may be increased to three times per day. Never increase your dosage without prior consent from your family doctor.
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